Semaglutide’s Heart Benefits Go Beyond the Scale, New Study Finds

Heart Benefits of Semaglutide Beyond Weight Loss

Research shows that semaglutide, an obesity medication, offers significant heart protection even when weight loss is minimal.

A new analysis of the SELECT trial found that semaglutide reduced the risk of heart attacks and other major events in people with obesity and cardiovascular disease,

even when people hadn’t lost much weight at all
.

The cardioprotective effects of semaglutide may be independent of weight loss, with

about a third of the benefit tied to fat loss
, and the bulk stemming from other mechanisms.

Author's summary: Semaglutide offers heart benefits beyond weight loss.

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South Florida Reporter South Florida Reporter — 2025-10-25

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