Scientists have discovered a surprising connection between long-term melatonin use and heart failure in patients with chronic insomnia.
Melatonin, often referred to as "nature's sleep switch," has become a popular nightly habit for millions of people.
Marketed as nature’s sleep switch, melatonin has become a nightly habit for millions.
A recent study presented at the American Heart Association's Scientific Sessions 2025 found that long-term melatonin use (for a year or more) in over 130,000 adults with insomnia was associated with:
Author's summary: Melatonin may harm heart health in insomnia patients.