Key Nervous System Components Influence Gastrointestinal Tumor Growth
Research has found that common nervous system components are present in the gastrointestinal tract, influencing tumor growth and revealing new opportunities for cancer treatment.
The gut has its own nervous system, often referred to as the "second brain". Key players in this system are neuropeptides, signaling factors produced and released by nerves, which relay messages throughout the nervous system by connecting to receptors on the outside of cells.
- CGRP, a common neuropeptide, and its receptor RAMP1 have been found to influence tumor growth in colorectal and stomach cancers.
Our gut contains its very own nervous system and is commonly regarded as the second brain.
A team at the Olivia Newton-John Cancer Research Institute (ONJCRI) and La Trobe School of Cancer Medicine made this discovery, creating promising new avenues for treatment with existing approved therapies.
Author's summary: New research reveals nervous system components influence gastrointestinal tumor growth.
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